The Supreme Anna Nicole Smith T-shirt was released in seven different colors as a part of the brand's Spring Tees release, which took place in Week 8 of their Spring/Summer 2021 Season.

The Spring/Summer 2021 Supreme Spring Tees release included seven new graphic t-shirts that featured imagery like an illustrated dominatrix bear, a t-shirt featuring Miles Davis, and what might have been a loose Michael Jordan reference. The Supreme Anna Nicole Smith T-shirt features an image of the late actress, model, and TV personality above a Supreme logo.

This Supreme T-shirt was made available on April 15th, 2021, at the retail price of $48 USD.